diff --git a/add-riscv-support.patch b/add-riscv-support.patch
new file mode 100644
index 0000000..974a5a1
--- /dev/null
+++ b/add-riscv-support.patch
@@ -0,0 +1,19 @@
+Author: misaka00251 <liuxin@iscas.ac.cn>
+Date:   Wed Sep 21 11:15:51 2022 +0800
+
+	Fix support for RISC-V.
+
+diff --git a/c++/src/build-system/config.guess b/c++/src/build-system/config.guess
+index f475ceb..57481db 100755
+--- a/c++/src/build-system/config.guess
++++ b/c++/src/build-system/config.guess
+@@ -979,6 +979,9 @@ EOF
+     ppc:Linux:*:*)
+ 	echo powerpc-unknown-linux-gnu
+ 	exit ;;
++	riscv32:Linux:*:* | riscv32be:Linux:*:* | riscv64:Linux:*:* | riscv64be:Linux:*:*)
++	echo ${UNAME_MACHINE}-unknown-linux-gnu
++	exit ;;
+     s390:Linux:*:* | s390x:Linux:*:*)
+ 	echo ${UNAME_MACHINE}-ibm-linux
+ 	exit ;;
diff --git a/ncbi-blast.spec b/ncbi-blast.spec
index 5941a5e..7521f42 100644
--- a/ncbi-blast.spec
+++ b/ncbi-blast.spec
@@ -1,10 +1,13 @@
 Name:                ncbi-blast
 Version:             2.12.0
-Release:             2
+Release:             3
 Summary:             NCBI BLAST finds regions of similarity between biological sequences.
 License:             Public Domain
 URL:                 https://blast.ncbi.nlm.nih.gov/Blast.cgi
 Source0:             https://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/2.12.0/ncbi-blast-2.12.0+-src.tar.gz
+%ifarch riscv64
+Patch0:              add-riscv-support.patch
+%endif
 BuildRequires:       lmdb lmdb-devel gcc-c++ make
 %description
 The NCBI Basic Local Alignment Search Tool (BLAST) finds regions of
@@ -43,6 +46,9 @@ cp c++/ReleaseMT/lib/* %{buildroot}%{_libdir}/ncbi-blast/
 %{_libdir}/ncbi-blast/*
 
 %changelog
+* Thu Nov 24 2022 misaka00251 <liuxin@iscas.ac.cn> - 2.12.0-3
+- Add riscv support
+
 * Tue Feb 15 2022 herengui <herengui@uniontech.com> - 2.12.0-2
 - add missing buildrquires.